服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | PJ 34 hydrochloride |
Chemical Name | PJ 34 hydrochloride |
CAS Number | [344458-15-7] |
Mol. Formula | C17H17N3O2.HCl |
Mol. Weight | 331.8 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-(5,6-Dihydro-6-oxo-2-phenanthridi nyl)-2-acetamide hydrochloride |
Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at RT |
References | Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ~ 1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Purity: >98 % |