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| Cat. Number | PIT 1 |
| Chemical Name | PIT 1 |
| CAS Number | [53501-41-0] |
| Mol. Formula | C14H10ClN3O4S |
| Mol. Weight | 351.76 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[[(3-Chloro-2-hydroxy-5-nitrophen yl)amino]thioxomethyl]benzamide |
| Solubility | Soluble to 75 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Selective PIP3 antagonist. Blocks the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50 = 31.03 μM). Inhibits cancer cell survival and induces apoptosis by inhibition of PIP3-dependent PI 3-kinase/Akt signaling. Exhibits antitumor activity in vivo. Purity: >99 % |
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