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Cat. Number
PF 573228
Chemical Name
PF 573228
CAS Number
[869288-64-2]
Mol. Formula
C22H20F3N5O3S
Mol. Weight
491.49
Qty 1
10mg
Qty 2
50mg
Synonym
3,4-Dihydro-6-[[4-[[[3-(methylsulfo nyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyr imidinyl]amino]-2(1H)-quinolinone
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at +4°C
References
Potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). Displays 50 - 250-fold selectivity over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro.
Purity: >98 %
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