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/ Products Classification 点击展开+Cat. Number | PF 573228 |
Chemical Name | PF 573228 |
CAS Number | [869288-64-2] |
Mol. Formula | C22H20F3N5O3S |
Mol. Weight | 491.49 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 3,4-Dihydro-6-[[4-[[[3-(methylsulfo nyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyr imidinyl]amino]-2(1H)-quinolinone |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at +4°C |
References | Potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). Displays 50 - 250-fold selectivity over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro. Purity: >98 % |