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Cat. Number
RS 25344 hydrochloride
Chemical Name
RS 25344 hydrochloride
CAS Number
[152814-89-6]
Mol. Formula
C19H13N5O4.HCl
Mol. Weight
411.8
Qty 1
10mg
Qty 2
50mg
Synonym
1-(3-Nitrophenyl)-3-(4-pyridinylmet hyl)-pyrido[2,3-d]pyrimidine-2,3-(1H,3H)-dione hydrochloride
Solubility
Soluble to 50 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 values are 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively). Inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.
Purity: >98 %
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