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/ Products Classification 点击展开+Cat. Number | Ro 32-3555 |
Chemical Name | Ro 32-3555 |
CAS Number | [190648-49-8] |
Mol. Formula | C22H35N4O5 |
Mol. Weight | 436.55 |
Qty 1 |
10mg |
Synonym | (αR,βR)-β-(Cyclopentylmethyl)-N-hydrox y-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidin yl)methyl]-1-piperidinebutanamide |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at -20°C |
References | Potent, collagenase-selective MMP inhibitor (Ki values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3 respectively). Inhibits cartilage breakdown in vitro and in vivo and displays antiarthritic activity. Orally active. Purity: >97 % |
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