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Cat. Number
Ro 32-3555
Chemical Name
Ro 32-3555
CAS Number
[190648-49-8]
Mol. Formula
C22H35N4O5
Mol. Weight
436.55
Qty 1
10mg
Synonym
(αR,βR)-β-(Cyclopentylmethyl)-N-hydrox y-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidin yl)methyl]-1-piperidinebutanamide
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at -20°C
References
Potent, collagenase-selective MMP inhibitor (Ki values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3 respectively). Inhibits cartilage breakdown in vitro and in vivo and displays antiarthritic activity. Orally active.
Purity: >97 %
下一个:Ro 3306上一个:Ro 32-0432 hydrochloride
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