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Cat. Number
SU 16f
Chemical Name
SU 16f
CAS Number
[251356-45-3]
Mol. Formula
C24H22N2O3
Mol. Weight
386.44
Qty 1
10mg
Qty 2
50mg
Synonym
5-[1,2-Dihydro-2-oxo-6-phenyl-3H-in dol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-pr opanoic acid
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM).
Purity: >98 %
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