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| Cat. Number | SU 11274 |
| Chemical Name | SU 11274 |
| CAS Number | [658084-23-2] |
| Mol. Formula | C28H30ClN5O4S |
| Mol. Weight | 568.09 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (3Z)-N-(3-Chlorophenyl)-3-[[3,5-dim ethyl-4-[(4-methyl-1-piperazinyl)carbonyl]-1H-pyrr ol-2-yl]methylene]-2,3-dihydro-N-methyl-2-oxo-1H-i ndole-5-sulfonamide |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Selective inhibitor of MET tyrosine kinase activity (IC50 = 0.01 μM in vitro). Reduces cell growth in a dose-dependent manner; induces cell cycle arrest and apoptosis. Abrogates cell motility and migration in vitro and tumor angiogenesis in vivo. Purity: >97 % |
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