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| Cat. Number | SD 208 |
| Chemical Name | SD 208 |
| CAS Number | [627536-09-8] |
| Mol. Formula | C17H10ClFN6 |
| Mol. Weight | 352.75 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-(5-Chloro-2-fluorophenyl)-4-[(4-p yridyl)amino]pteridine |
| Solubility | Soluble to 20 mM in DMSO |
| Storage condition | Store at RT |
| References | Potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50 = 49nM). Displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. Exhibits anti-inflammatory and antitumor activity. Purity: >98 % |
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