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Cat. Number
SD 169
Chemical Name
SD 169
CAS Number
[1670-87-7]
Mol. Formula
C9H8N2O
Mol. Weight
160.17
Qty 1
10mg
Qty 2
50mg
Synonym
1H-Indole-5-carboxamide
Solubility
Soluble to 10 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
Selective, orally active, ATP-competitive inhibitor of p38α MAPK (IC50 values are 3.2, 122 and > 50000 nM for p38α, p38β and p38γ respectively). Demonstrates no activity against a range of other kinases including ERK2, JNK1 and MAPKAP2. Prevents development of diabetes and alleviates mild and moderate hyperglycaemic states in NOD mice.
Purity: >98 %
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