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/ Products Classification 点击展开+Cat. Number | SD 169 |
Chemical Name | SD 169 |
CAS Number | [1670-87-7] |
Mol. Formula | C9H8N2O |
Mol. Weight | 160.17 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 1H-Indole-5-carboxamide |
Solubility | Soluble to 10 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | Selective, orally active, ATP-competitive inhibitor of p38α MAPK (IC50 values are 3.2, 122 and > 50000 nM for p38α, p38β and p38γ respectively). Demonstrates no activity against a range of other kinases including ERK2, JNK1 and MAPKAP2. Prevents development of diabetes and alleviates mild and moderate hyperglycaemic states in NOD mice. Purity: >98 % |