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Cat. Number
SC 560
Chemical Name
SC 560
CAS Number
[188817-13-2]
Mol. Formula
C17H12ClF3N2O
Mol. Weight
352.74
Qty 1
10mg
Synonym
5-(4-Chlorophenyl)-1-(4-methoxyphen yl)-3-(trifluoromethyl)-1H-pyrazole
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at +4°C
References
Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 μM for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production. Significantly reduces ovarian surface epithelial tumor growth in vivo. Orally active.
Purity: >98 %
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