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| Cat. Number | SB 431542 |
| Chemical Name | SB 431542 |
| CAS Number | [301836-41-9] |
| Mol. Formula | C22H16N4O3 |
| Mol. Weight | 384.39 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Synonym | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-py ridinyl)-1H-imidazol-2-yl]benzamide |
| Solubility | Soluble to 10 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Store at RT |
| References | Potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. Suppresses TGF-β-induced proliferation of human osteosarcoma cells. Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells. Purity: >99 % |
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