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| Cat. Number | SB 415286 |
| Chemical Name | SB 415286 |
| CAS Number | [264218-23-7] |
| Mol. Formula | C16H10ClN3O5 |
| Mol. Weight | 359.73 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-[(3-Chloro-4-hydroxyphenyl)amino] -4-(2-nitrophenyl)-1H-pyrrole-2,5-dione |
| Solubility | Soluble to 25 mM in ethanol and to 50 mM in DMSO |
| Storage condition | Store at RT |
| References | Potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 31 nM for GSK-3α); competes with ATP. Has minimal activity against 24 other protein kinases (IC50 > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective. Purity: >99 % |
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