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Cat. Number
SB 328437
Chemical Name
SB 328437
CAS Number
[247580-43-4]
Mol. Formula
C21H18N2O5
Mol. Weight
378.38
Qty 1
10mg
Qty 2
50mg
Synonym
N-(1-Naphthalenylcarbonyl)-4-nitro- L-phenylalanine methyl ester
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at +4°C
References
Potent and selective CCR3 antagonist (IC50 = 4 nM). Displays > 2500-fold selectivity over C5aR, LTD4, CCR7, CXCR1 and CXCR2 receptors. Inhibits eotaxin-, eotaxin-2- and MCP-4-induced Ca2+ mobilization (IC50 values are 38, 35 and 20 nM respectively) and inhibits eotaxin-, eotaxin-2- and MCP-4-induced eosinophil chemotaxis with similar potencies.
Purity: >99 %
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