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| Cat. Number | SB 297006 |
| Chemical Name | SB 297006 |
| CAS Number | [58816-69-6] |
| Mol. Formula | C18H18N2O5 |
| Mol. Weight | 342.35 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-Benzoyl-4-nitroaniline ethyl ester |
| Solubility | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| Storage condition | Store at RT |
| References | Potent and selective CCR3 antagonist (IC50 = 39 nM). Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 >27 μM). Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210 nM respectively). Purity: >99 % |
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