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| Cat. Number | SB 216763 |
| Chemical Name | SB 216763 |
| CAS Number | [280744-09-4] |
| Mol. Formula | C19H12Cl2N2O2 |
| Mol. Weight | 371.22 |
| Qty 1 |
1mg |
| Qty 2 | 50mg |
| Synonym | 3-(2,4-Dichlorophenyl)-4-(1-methyl- 1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Solubility | Soluble to 75 mM in DMSO |
| Storage condition | Store at RT |
| References | Potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 9 nM for GSK-3α); competes with ATP. Has minimal activity against 24 other protein kinases (IC50 > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective. Also reduces pulmonary inflammation and fibrosis in a mouse model. Purity: >99 % |
下一个：SB 218078上一个：SB 216641 hydrochloride |
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