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| Cat. Number | SB 203580 hydrochloride |
| Chemical Name | SB 203580 hydrochloride |
| CAS Number | [152121-47-6] |
| Mol. Formula | C21H16FN3OS.HCl |
| Mol. Weight | 413.89 |
| Qty 1 |
10mg |
| Synonym | 4-[5-(4-Fluorophenyl)-2-[4-(methyls ulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride |
| Solubility | Soluble to 25 mM in water |
| Storage condition | Desiccate at -20°C |
| References | Water-soluble salt of SB 203580 (Cat. No. 1202). Selective inhibitor of p38 mitogen-activated protein kinase (IC50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK3β and PKBα. Shown to inhibit interleukin-2-induced T-cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. Purity: >98 % |
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