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Cat. Number
733985273868036
Chemical Name
Sorafenib-methyl-d3
Category
Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C21H13D3ClF3N4O3
Mol. Weight
467.84
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White to Light Pink Solid
Application Notes
Labelled Sorafenib, a potent RAF kinase inhibitor. Antineoplastic.
Synonym
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-(methyl-d3)-2-pyridinecarboxamide; BAY-43-9006-d3;
Melting Pt.
202-204?C
Solubility
Dichloromethane, Ethyl Acetate, Methanol (Sparingly)
Storage condition
-20?C Freezer
References
Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),
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