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Cat. Number
733985126419773
Chemical Name
Sorafenib
CAS Number
284461-73-0
Category
Amines, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C21H16ClF3N4O3
Mol. Weight
464.82
Qty 1
5mg
Qty 2
50mg
Appearance
Light Yellow Solid
Application Notes
Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
Synonym
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide; BAY-43-9006;
Melting Pt.
202-204°C
Solubility
DMSO, Hot Methanol
Storage condition
-20?C Freezer
References
Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),
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