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/ Products Classification 点击展开+Cat. Number | 733985126419773 |
Chemical Name | Sorafenib |
CAS Number | 284461-73-0 |
Category | Amines, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, |
Mol. Formula | C21H16ClF3N4O3 |
Mol. Weight | 464.82 |
Qty 1 |
5mg |
Qty 2 | 50mg |
Appearance | Light Yellow Solid |
Application Notes | Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic. |
Synonym | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide; BAY-43-9006; |
Melting Pt. | 202-204°C |
Solubility | DMSO, Hot Methanol |
Storage condition | -20?C Freezer |
References | Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006), |