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/ Products Classification 点击展开+Cat. Number | 733983973601844 |
Chemical Name | Nitisinone-13C6 |
Category | Aromatics, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals |
Mol. Formula | C813C6H10F3NO5 |
Mol. Weight | 335.18 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Appearance | Tan Solid |
Application Notes | Labelled Nitisinone. Herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I. |
Synonym | 2-[2-Nitro-4-(trifluoromethyl)benzoyl]- 1,3-cyclohexanedione -13C6; NTBC-13C6; Nitisone-13C6; Orfadin-13C6; SC 0735-13C6;
|
Melting Pt. | 132-134?C |
Solubility | Chloroform, Ethyl Acetate |
Storage condition | -20?C Freezer |
References | Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998), |