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/ Products Classification 点击展开+| Cat. Number | 733979612149843 |
| Chemical Name | Ketoconazole-d8 |
| Category | Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Mol. Formula | C26H20D8Cl2N4O4 |
| Mol. Weight | 539.48 |
| Qty 1 |
2.5mg |
| Qty 2 | 25mg |
| Appearance | White to Off-White Solid |
| Application Notes | Deuterated Ketoconazole, an inhibitor of cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. |
| Synonym | cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-d8 |
| Melting Pt. | 140-144oC |
| Solubility | Chloroform, Dichloromethane, DMSO |
| Storage condition | -20?C Freezer |
| References | Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986) |
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