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/ Products Classification 点击展开+Cat. Number | 733979104137915 |
Chemical Name | Ketoconazole |
CAS Number | 65277-42-1 |
Category | Pharmaceuticals, Intermediates & Fine Chemicals, Inhibitors, |
Mol. Formula | C26H28Cl2N4O4 |
Mol. Weight | 531.44 |
Qty 1 |
500mg |
Qty 2 | 5g |
Appearance | White Powder |
Application Notes | Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. |
Synonym | cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine |
Melting Pt. | 144-146oC |
Solubility | Chloroform |
Storage condition | -20?C Freezer |
References | Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986) |