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Cat. Number
733979104137915
Chemical Name
Ketoconazole
CAS Number
65277-42-1
Category
Pharmaceuticals, Intermediates & Fine Chemicals, Inhibitors,
Mol. Formula
C26H28Cl2N4O4
Mol. Weight
531.44
Qty 1
500mg
Qty 2
5g
Appearance
White Powder
Application Notes
Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.
Synonym
cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
Melting Pt.
144-146oC
Solubility
Chloroform
Storage condition
-20?C Freezer
References
Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)
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