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Cat. Number
733976637490159
Chemical Name
Entacapone-d10
Category
Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C14H5D10N3O5
Mol. Weight
315.35
Qty 1
1mg
Qty 2
10mg
Appearance
Yellow Crystalline Solid
Application Notes
(E)-Isomer of labelled Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
Synonym
(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-di-(ethyl-d5)-2-propenamide; OR-611-d10; Comtan-d10; Comtess-d10;
Melting Pt.
162-1630C
References

Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992),
Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992),
Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),

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