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| Cat. Number | 733974507449067 |
| Chemical Name | N-Desmethyl Imatinib |
| CAS Number | 404844-02-6 |
| Category | Metabolites, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |
| Mol. Formula | C28H29N7O |
| Mol. Weight | 479.58 |
| Qty 1 |
0.5mg |
| Qty 2 | 5mg |
| Appearance | Off-White to Pale-Yellow Solid |
| Application Notes | A metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). |
| Synonym | N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide; N-Desmethyl Gleevec; CGP-74588; Norimatinib; STI 509-00; |
| Melting Pt. | 183-185°C |
| Boiling Pt. | N/A |
| Solubility | Chloroform, Dichloromethane |
| Storage condition | -20°C Freezer |
| References |
Schindler, T., et al.: Science, 289, 1938 (2000), |
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