服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | 733968406822253 |
Chemical Name | A77 1726-d4 |
CAS Number | 1185240-22-5 |
Category | Isotope Labelled Compounds, Metabolites & Impurities, Tyrosine Kinase Inhibitors, |
Mol. Formula | C12H5D4F3N2O2 |
Mol. Weight | 274.23 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Appearance | Off-White Solid |
Application Notes | The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. |
Synonym | N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide-d4, LEF-M-d4; Teriflunomide-d4 |
Melting Pt. | 214-217?C |
Solubility | DMSO, Aqueous Alkali |
References | Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005) |