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Cat. Number
733968406822253
Chemical Name
A77 1726-d4
CAS Number
1185240-22-5
Category
Isotope Labelled Compounds, Metabolites & Impurities, Tyrosine Kinase Inhibitors,
Mol. Formula
C12H5D4F3N2O2
Mol. Weight
274.23
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White Solid
Application Notes
The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.
Synonym
N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide-d4, LEF-M-d4; Teriflunomide-d4
Melting Pt.
214-217?C
Solubility
DMSO, Aqueous Alkali
References
Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)
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