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/ Products Classification 点击展开+| Cat. Number | 733968330884842 |
| Chemical Name | A77 1726 |
| CAS Number | 163451-81-8 |
| Category | Metabolites & Impurities, Tyrosine Kinase Inhibitors, |
| Mol. Formula | C12H9F3N2O2 |
| Mol. Weight | 270.21 |
| Qty 1 |
10mg |
| Qty 2 | 100mg |
| Appearance | White Solid |
| Application Notes | The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. |
| Synonym | N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M; Teriflunomide |
| Melting Pt. | 229-232°C |
| Solubility | DMSO, Methanol |
| Storage condition | Hygroscopic, -20?C Freezer, Under Inert Atmosphere |
| References | Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005) |
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