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Cat. Number
733968406939904
Chemical Name
Amrubicinol-13C2,15N (Mixture of Diastereomers)
Category
Carbohydrates & Derivatives, Chiral Reagents, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C2313C2H2715NO9
Mol. Weight
488.46
Qty 1
0.5mg
Qty 2
5mg
Appearance
Red Solid
Application Notes
A labelled metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug.
Synonym
(7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione-13C2,15N; 13-Hydroxy SM 5887-13C2,15N;
Solubility
Methanol
Storage condition
-20?C Freezer, Under Inert Atmosphere
References
Oken, M., et al.: Am. J. Clin. Oncol., 5, 649 (1982), Ohara, H., et al.: Biochem. Pharmacol., 50, 221 (1995), de Jongh, F., et al.: J. Clin. Oncol., 19, 3733 (2001), Backstrom, G., et al.: Eur. J. Pharm. Sci., 18, 359 (2003),
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