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/ Products Classification 点击展开+Cat. Number | 733968304647076 |
Chemical Name | Amrubicinol (Mixture of Diastereomers) |
CAS Number | 186353-53-7 |
Category | Carbohydrates & Derivatives, Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |
Mol. Formula | C25H27NO9 |
Mol. Weight | 485.48 |
Qty 1 |
1mg |
Application Notes | A metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. |
Synonym | (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione; 13-Hydroxy SM 5887; |
References | Oken, M., et al.: Am. J. Clin. Oncol., 5, 649 (1982), Ohara, H., et al.: Biochem. Pharmacol., 50, 221 (1995), de Jongh, F., et al.: J. Clin. Oncol., 19, 3733 (2001), Backstrom, G., et al.: Eur. J. Pharm. Sci., 18, 359 (2003), |