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Cat. Number
733968304647076
Chemical Name
Amrubicinol (Mixture of Diastereomers)
CAS Number
186353-53-7
Category
Carbohydrates & Derivatives, Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C25H27NO9
Mol. Weight
485.48
Qty 1
1mg
Application Notes
A metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug.
Synonym
(7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione; 13-Hydroxy SM 5887;
References
Oken, M., et al.: Am. J. Clin. Oncol., 5, 649 (1982), Ohara, H., et al.: Biochem. Pharmacol., 50, 221 (1995), de Jongh, F., et al.: J. Clin. Oncol., 19, 3733 (2001), Backstrom, G., et al.: Eur. J. Pharm. Sci., 18, 359 (2003),
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