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Cat. Number
10-4508
Chemical Name
10-4508 SR1 1227633-49-9
CAS Number
1227633-49-9
Mol. Formula
C24H23N5OS
Mol. Weight
466
Qty 1
1mg
Qty 2
5mg
Appearance
Off-white solid
Application Notes
99% by HPLC NMR (Conforms)
Solubility
Soluble in DMSO (up to 10 mg/ml).
Storage condition
-20℃
Stability
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
References

SR1 (1227633-49-9) extends the pluripotency of hematopoietic stem cells (IC50 = 127 nM) by antagonizing AhR signaling resulting in continued expression of CD34. Effects are easily reversed by the removal of the SR1.

References/Citations
1) Boitano et al. (2010), Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells; Science, 329 1354

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