您的位置:首页>>生化试剂>>小分子化合物>>10-2416 N-[2-Amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate 75507-68-5
Cat. Number
10-2416
Chemical Name
10-2416 N-[2-Amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate 75507-68-5
CAS Number
75507-68-5
Mol. Formula
C15H17FN4O2 • C4H4O4
Mol. Weight
420.39
Qty 1
50mg
Qty 2
100mg
Appearance
White solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
D9998
Solubility
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml)
Storage condition
RT
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
References

flupirtine maleate (75507-68-5) activates KV7 potassium channels1, indirectly antagonizes NMDA receptors and modulates GABAA receptors2. Displays neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli. Analgesic activity.3 Active in vivo.
 

References/Citations

1) Azad et al. (2004), The potassium channel modulator flupirtine shifts the frequency-response function of hippocampal synapses to favour LTD in mice; Neuro. Sci. Lett., 370 186
2) Klinger et al. (2012), Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine; Br. J. Pharmacol., 166 1631
3) Osbourne et al. (1998), Flupirtine, a nonopioid centrally acting analgesic, acts as an NMDA antagonist; Gen. Pharmacol., 30 255

Image 1

氟吡汀马来酸盐  英文名称Flupirtine maleate ,货号10-2416 上海惠诚提供100mg 50mg 氟吡汀马来酸盐 Flupirtine maleate,美国focus原装进口,咨询电话021-60498804

氟吡汀马来酸盐  英文名称Flupirtine maleate ,货号10-2416 上海惠诚提供100mg 50mg 氟吡汀马来酸盐 Flupirtine maleate,美国focus原装进口,咨询电话021-60498804

 

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