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Cat. Number
10-2274
Chemical Name
10-2274 DL-α-Difluoromethylornithine Hydrochloride Monohydrate 96020-91-6
CAS Number
96020-91-6
Mol. Formula
C6H12F2N2O2 HCl H2O
Mol. Weight
236.65
Qty 1
10mg
Qty 2
50mg
Appearance
White solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
DFMO; Eflornithine
Solubility
Soluble in Water (up to 25 mg/ml).
Storage condition
RT
Stability
Stable for 2 years as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
References

Difluoromethylornithine HCl (96020-91-6) is a selective inhibitor of ornithine decarboxylase.1 Induces apoptosis in a variety of cells.2 Difluoromethylornithine HCl displays cancer chemopreventive activity.3 Cell permeable. Active in vivo.

References/Citations
1) Verma et al. (1990), Inhibition of tumor promotion by DL-alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase; Basic Life Sci., 52 195
2) Takahashi et al. (2000), Alpha-difluoromethylornithine induces apoptosis as well as anti-angiogenesis in the inhibition of tumor growth and metastasis in a human gastric cancer model; Int. J. Cancer, 85 243
3) Meyskens et al. (1999), Development of difluoromethylornithine (DFMO) as a chemoprevention agent; Clin. Cancer Res., 5 945

Focus Biomolecules supplier, structure of Difluoromethylornithine HCl | Inhibits polyamine biosynthesis | CAS 96020-91-6

二氟甲基鸟氨酸盐酸盐  英文名称Difluoromethylornithine HCl ,货号10-2274上海惠诚提供10mg 50mg 二氟甲基鸟氨酸盐酸盐 Difluoromethylornithine HCl,美国focus原装进口,咨询电话021-60498804

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