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Cat. Number
10-2171
Chemical Name
10-2171 154-17-6
CAS Number
154-17-6
Mol. Formula
C6H12O5
Mol. Weight
164.16
Qty 1
1g
Qty 2
5g
Appearance
White solid
Application Notes
98%
Synonym
2-DG
Solubility
Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 15 mg/ml).
Storage condition
-20℃
Stability
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day.
References

2-Deoxy-D-glucose (154-17-6) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolysis, but its metabolic effects are wide-ranging. 2-Deoxy-D-glucose competitively inhibits glucose uptake via its metabolite 2-Deoxy-D-glucose-6-phosphate, which inhibits hexokinase and phosphoglucose-isomerase leading to decreased ATP production, cell cycle blockage, decreased cell growth and ultimately cell death.1,2

References/Citations
1) Ralser et al., (2008), A catabolic blockade does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth; Proc. Natl. Acad. Sci. USA 105 17807
2) Giammarioli et al. (2012), Differential effects of the glycolysis inhibitor 2-deoxy-D-glucose on the activity of pro-apoptotic agents in metastatic melanoma cells; Int. J. Cancer, 131 e337

Focus Biomolecules supplier, chemical structure of 2-Deoxy-D-Glucose | Biologically active glucose analog | CAS 154-17-6

2-脱氧-D-葡萄糖  英文名称2-Deoxy-D-Glucose ,货号10-2171 上海惠诚提供1g 5g2-脱氧-D-葡萄糖 2-Deoxy-D-Glucose,美国focus原装进口,咨询电话021-60498804

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