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| Cat. Number | 10-2137 |
| Chemical Name | 10-2137 1-(5-Isoquinolinesulfonyl)homopiperazine HCl 105628-07-7 |
| CAS Number | 105628-07-7 |
| Mol. Formula | C14H17N3O2S HCl |
| Mol. Weight | 327.84 |
| Qty 1 |
25mg |
| Qty 2 | 50mg |
| Appearance | White solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | HA-1077 |
| Solubility | Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml) |
| Storage condition | RT |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. |
| References | Fasudil HCl (105628-07-7) is a Rho-associated kinase inhibitor (IC50 = 1.9 μM and 10.7 μM for Rho-associated kinase II and Rho-associated kinase respectively)1. Inhibits other kinases including cyclic nucleotide-dependent protein kinases.1Fasudil HCl reduces tryptamine-evoked vasopressor responses.2 Attenuates bleomycin-induced pulmonary fibrosis in a mouse model.3 Clinically useful vasodilator.
References/Citations
Fasudil · HCl ，货号10-2137 上海惠诚提供25mg 50mg Fasudil · HCl，美国focus原装进口，咨询电话021-60498804 Fasudil · HCl ，货号10-2137 上海惠诚提供25mg 50mg Fasudil · HCl，美国focus原装进口，咨询电话021-60498804
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