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| Cat. Number | 10-2125 |
| Chemical Name | 10-2125 CI-994 112522-64-2 |
| CAS Number | 112522-64-2 |
| Mol. Formula | C15H15N3O2 |
| Mol. Weight | 269.30 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Appearance | Off-white solid |
| Application Notes | 98% by HPLC NMR (Conforms) |
| Synonym | 4-(Acetylamino)-N-(2-aminophenyl)benzamide,PD-123654; N-acetyl-dinaline; GOE-5549 |
| Solubility | Soluble in DMSO (up to 25 mg/ml) |
| Storage condition | -20°C (des.) |
| Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| References | CI-994 (112522-64-2) is an orally active histone deacetylase (HDAC) inhibitor, IC50 = 0.9, 0.9, 1.2 and >20 μM for HDAC1, HDAC2, HDAC3 and HDAC8 respectively.1Mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo.2,3 Increases neuroplasticity during memory extinction.4 Protects beta cells from cytokine-induced apoptosis.4 References/Citations
1) Moradei et al. (2007), Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity; J. Med. Chem., 50 5543
CI-994 ，货号10-2125上海惠诚提供10mg 50mg CI-994，美国focus原装进口，咨询电话021-60498804 |
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