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| Cat. Number | 10-1198 |
| Chemical Name | GSK-1016790A |
| CAS Number | 942206-85-1 |
| Mol. Formula | C28H32Cl2N4O6S2 |
| Mol. Weight | 655.62 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide |
| Solubility | Soluble in DMSO (up to 10 mg/ml). |
| Storage condition | -20℃ |
| Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| References | GSK-1016790A (942206-85-1) is a novel and potent TRPV4 channel agonist. GSK-1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300-fold more potent than 4α-PDD and is a valuable tool for investigating the role of TRPV4 in physiological processes.
References/Citations
GSK-1016790A ，货号10-1198上海惠诚提供5mg 25mg GSK-1016790A，美国focus原装进口，咨询电话021-60498804
GSK-1016790A ，货号10-1198上海惠诚提供5mg 25mg GSK-1016790A，美国focus原装进口，咨询电话021-60498804
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