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/ Products Classification 点击展开+Cat. Number | 10-1126 |
Chemical Name | 长春西汀 Vinpocetine |
CAS Number | 42971-09-5 |
Mol. Formula | C22H26N2O2 |
Mol. Weight | 350.45 |
Qty 1 |
20mg |
Qty 2 | 100mg |
Appearance | White solid |
Application Notes | 98% by TLC NMR (Conforms) |
Synonym | (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester |
Solubility | Soluble in DMSO (up to 5 mg/ml), in ethanol (up to 15 mg/ml) or in DMF (up to 3 mg/ml with warming) |
Storage condition | RT |
Stability | Stable for 1 year as supplied. Solutions in DMSO, Ethanol, or DMF may be stored at -20°C for up to 3 months. |
References | Vinpocetine (42971-09-5) is a phosphodiesterase PDE1 inhibitor (IC50=21 μM).1 Also blocks voltage-gated Na+ channels, IC50=44.2 μM (potency similar to phenytoin), a mechanism which may contribute to its neuroprotective and anticonvulsant activity.2 It reduces inflammatory IL-1β and TNF-α expression in rat hippocampus.3Displays beneficial effects in a rat model of cerebral ischemia-reperfusion injury.4Vinpocetine exerts neuroprotective effects by suppressing microglial inflammation.5 References/Citations
1) Hagiwara et al. (1984), Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle; Biochem. Pharmacol., 33 453
长春西汀 英文名称Vinpocetine ,货号10-1126 上海惠诚提供100mg 20mg 长春西汀 Vinpocetine,美国focus原装进口,咨询电话021-60498804 |