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/ Products Classification 点击展开+Cat. Number | C9613 |
Chemical Name | 环孢菌素D. Cyclosporin D |
CAS Number | 63775-96-2 |
Mol. Formula | C63H113N11O12 |
Mol. Weight | 1216.64 |
Qty 1 |
1mg |
Qty 2 | 5mg |
Appearance | White Crystalline Powder |
Application Notes | ≥98% |
Synonym | Val2-cyclosporine |
Melting Pt. | 148-151°C |
Solubility | Soluble in methanol, ethanol, acetone, ether, ethyl acetate or chloroform. Insoluble in water. |
Storage condition | Ambient |
References | Cyclosporin D is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin D exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and in vivo. 参考文献: Uadia PO, Ezeamuzie IC, Ladan MJ, et al. Antimalarial activity of cyclosporins A, C and D. Afr J Med Med Sci. 1994 Mar;23(1):47-51. PMID: 7839946. Sadeg N, Pham-Huy C, Rucay P, et al. In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):163-77. PMID: 8349948. |