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Cat. Number
Sulfo-Cyanine5 tetrazine
Chemical Name
Sulfo-Cyanine5 tetrazine
Mol. Formula
C42H46KN7O7S2
Mol. Weight
864.09
Qty 1
5mg
Qty 2
25mg
Appearance
dark blue solid
Solubility
good in water, DMF, DMSO
Storage condition
-20°C
References

TCO (tetrazine - trans-cyclooctene) ligation is one of the fastest reactions used for the bioconjugation. It is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.

Sulfo-Cyanine5 tetrazine is a fluorophore derivative bearing a tetrazine group for the TCO-ligation based labeling.

This reagent possesses good aqueous solubility and stability in biological environments.

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.13
CF280: 0.13
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