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Cat. Number
Cy5.5 马来酰亚胺 Cyanine5.5 maleimide
Chemical Name
Cy5.5 马来酰亚胺 Cyanine5.5 maleimide
Mol. Formula
C46H49ClN4O3
Mol. Weight
741.36
Qty 1
5mg
Qty 2
25mg
Appearance
dark blue powder
Solubility
soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Storage condition
-20°C
References

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 209000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Wilks, M.Q.; Normandin, M.D.; Yuan, H.; Cho, H.; Guo, Y.; Herisson, F.; Ayata, C.; Wooten, D.W.; El Fakhri, G.; Josephson, L. Imaging PEG-Like Nanoprobes in Tumor, Transient Ischemia, and Inflammatory Disease Models. Bioconjugate Chemistry2015, 26(6), 1061–1069. doi: 10.1021/acs.bioconjchem.5b00213

  2. Cai, H.; Singh, A.N.; Sun, X.; Peng, F. Synthesis and Characterization of Her2-NLP Peptide Conjugates Targeting Circulating Breast Cancer Cells: Cellular Uptake and Localization by Fluorescent Microscopic Imaging. Journal of Fluorescence2015, 25(1), 113–117. doi: 10.1007/s10895-014-1486-9

  3. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation2014, 10(12), 5505-5512. doi: 10.1021/ct500869p

  4. Park, S.; Kim, Y.-J.; Jon, S. A high-affinity peptide for nicotinic acetylcholine receptor-α1 and its potential use in pulmonary drug delivery. Journal of Controlled Release2014, 192, 141-147. doi:10.1016/j.jconrel.2014.07.006

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