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Cat. Number
H1320
Chemical Name
H1320 N,N-Dimethyl-D-erythro-sphingosine (Inhibitor of Phosphokinase C) 119567-63-4
CAS Number
119567-63-4
Category
synthetic
Mol. Formula
C20H41NO2
Mol. Weight
328
Qty 1
1mg
Appearance
liquid
Application Notes
98+% TLC
Synonym
N,N-Dimethylsphingosine
Solubility
ethanol, isopropanol, chloroform, methanol
Storage condition
-20°C
References

1. J. Kim et al. “Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases” Bioorg Med Chem, Vol. 13 pp. 3475-3485, 2005
2. Y. Igarashi et al. “A Specific Enhancing Effect of N,N-Dimethylsphingosine on Epidermal Growth Factor Receptor Autophosphorylation” Journal of Biological Chemistry, Vol. 265(10) pp. 5385-5389, 1990
3. Z. Jin and J. Karliner “Low dose N, N-dimethylsphingosine is cardioprotective and activates cytosolic sphingosine kinase by a PKC dependent mechanism” Journal of Cardiovascular Research, Vol. 71(4) pp. 725-734, 2006
4. R. McDonald et al. “The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia” British Journal of Pharmacology, Vol. 159(3) pp. 543-553, 2010
下一个：D-鞘氨醇 D-erythro-Sphingosine上一个：L-threo-Sphingosylphosphorylcholine
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