H1526 岩藻糖单唾液酸神经节苷酯 Fucosylated monosialoganglioside GM1;Fucosyl-GM1 71812-11-8_上海惠诚生物生物试剂,标准品,仪器设备,耗材,一站式服务

服务热线：13917250134「同微信」

您的位置：首页>>分析化学>>脂类分析标准品>>H1526 岩藻糖单唾液酸神经节苷酯 Fucosylated monosialoganglioside GM1;Fucosyl-GM1 71812-11-8

产品中心

/ Products Classification 点击展开+

Cat. Number	H1526
Chemical Name	H1526 岩藻糖单唾液酸神经节苷酯 Fucosylated monosialoganglioside GM1;Fucosyl-GM1 71812-11-8
CAS Number	71812-11-8
Category	natural
Mol. Formula	C₇₉H₁₄₁N₃O₃₅•NH₃
Mol. Weight	1693
Qty 1	500ug
Appearance	solid
Application Notes	98+% TLC
Synonym	Fucosyl-GM1
Solubility	chloroform/methanol/water, 2:1:0.1; forms micellar solution in water
Storage condition	-20°C
References	1. L. Svennerholm, et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980 2. T. Kolter, R. Proia, K. Sandhoff, Combinatorial Ganglioside Biosynthesis. J. Biol. Chem., July Vol. 277, No. 29, pp. 25859-25862, 2002 3. G. Ragupathi et al. “Immunization of mice with fucosyl-GM1 conjugated with keyhole limpet hemocyanin results in antibodies against human small-cell lung cancer cells” Cancer Immunology, Immunotherapy, Vol. 48 pp. 483-492, 1999 4. M. Yanagisawa, T. Ariga, R. Yu “Fucosyl-GM1 expression and amyloid-β protein accumulation in PC12 cells” Journal of Neuroscience Research, Vol. 84 pp. 1343-1349, 2006 Gangliosides1 are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system.2 They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis. Fucosyl-GM1 is a tumor associated ganglioside and is an antigen expressed in small cell lung cancer that is being investigated as a target for vaccines against cancer cells.3 It has been found that Fucosyl-GM1 demonstrates some of the same binding properties as the similar GM1 ganglioside such as affinity for cholera toxin B subunit and interaction with amyloid-beta protein.4
下一个：神经三已糖基神经酰胺 Gangliotriosylceramide上一个：双唾液酸神经节苷脂GD3,Disialoganglioside GD3 (NH4+salt);GD3

联系我们

电话：021-60498804
邮箱：info@e-biochem.com
地址：上海市徐汇区漕溪路258弄27号航星商务楼2-404

扫一扫，关注我们

惠诚品牌

产品中心: 分子生物; 分析化学; 生化试剂; 仪器耗材

企业动态

技术资料

Copyright © 2022 上海惠诚生物科技有限公司沪ICP备2021037845号-6

在线咨询联系方式二维码

服务热线

021-60498804

扫一扫，关注我们