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Cat. Number
H1537
Chemical Name
H1537 N-C18:0-D3-神经鞘氨醇己三糖苷 N-Octadecanoyl-D3-ceramide trihexoside, deuterated
Category
semisynthetic
Mol. Formula
C54H98D3NO18
Mol. Weight
1055
Qty 1
0.5mg
Appearance
solid
Application Notes
98+% TLC
Synonym
N-C18:0-D3-CTH, deuterated; N-C18:0-D3-Gb3, deuterated; N-Octadecanoyl-D3-globotriaosylceramide, deuterated; N-Stearoyl-D3-ceramide trihexoside, deuterated
Solubility
chloroform/methanol, 2:1; DMSO
Storage condition
-20°C
References

1. S. Ashkenazi and T. G. Cleary, “Rapid method to detect shiga toxin and shiga-like toxin I based on binding to globotriosyl ceramide (Gb3), their natural receptor.” J Clin Microbio. June; 27(6): 1145-1150, 1989
2. S. Bekri, O. Lidove, R. Jaussaud, B. Knebelmann, F. Barbey. "The role of ceramide trihexoside (globotriaosylceramide) in the diagnosis and follow-up of the efficacy of treatment of Fabry disease: a review of the literature". Cardiovasc Hematol Agents Med Chem 4 (4): 289–97, October 2006
3. J. E. Groener, B. J. Poorthuis, S. Kuiper, M. T. Helmond, C. E. Hollak, J. M. Aerts. “HPLC for simultaneous quantification of total ceramide, glucosylceramide, and ceramide trihexoside concentrations in plasma.” Clin Chem., Apr;53(4):742-7, 2007. Epub Mar 1 2007
4. K. Mills, A. Johnson, B. Winchester. “Synthesis of novel internal standards for the quantitative determination of plasma ceramide trihexoside in Fabry disease by tandem mass spectrometry.” FEBS Lett., Mar 27;515(1-3):171-6, 2002
5. C. Menge, I. Stamm, M. Wuhrer, R. Geyer, L. H. Wieler, G. Baljer. “Globotriaosylceramide (Gb(3)/CD77) is synthesized and surface expressed by bovine lymphocytes upon activation in vitro.” Vet Immunol Immunopathol., Nov;83(1-2):19-36, 2001
下一个：3-Hydroxydecanoic acid上一个：N-Tricosanoyl ceramide trihexoside
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