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Cat. Number
H1720
Chemical Name
H1720 D,L-threo-PPMP 149022-18-4
CAS Number
149022-18-4
Category
synthetic
Mol. Formula
C29H50N2O3•HCI
Mol. Weight
511
Qty 1
100mg
Appearance
solid
Application Notes
98+% TLC
Synonym
D,L-threo-l-Phenyl-2-hexadecanoylamino-3-morpholino-propanol·HClActivity: glucosylceramide synthase inhibitor
Solubility
alcohols, chloroform
Storage condition
-20°C
References

1. B. Maurer et al. “Synergistic Cytotoxicity in Solid Tumor Cell Lines Between N-(4-Hydroxyphenyl)retinamide and Modulators of Ceramide Metabolism” Journal of the National Cancer Institute, Vol. 92(23) pp. 1897-1909, 2000
2. A. Puri et al. “Human Erythrocyte Glycolipids Promote HIV-1 Envelope Glycoprotein-Mediated Fusion of CD4+Cells” Biochemical and Biophysical Research Communications, Vol. 242 pp. 219-225, 1998
3. A. Couto et al. “Glycosphingolipids in Plasmodium falciparum: Presence of an active glucosylceramide synthase” European Journal of Biochemistry, Vol. 271 pp. 2204-2214, 2004
4. D. Sillance et al. “Glucosylceramide modulates membrane traffic along the endocytic pathway” Journal of Lipid Research, Vol. 43 pp. 1837-1845, 2002
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