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Cat. Number
H1832
Chemical Name
H1832 N-硬脂酰神经鞘氨醇 N-Octadecanoyl-D-erythro-sphingosine 2304-81-6
CAS Number
2304-81-6
Category
synthetic
Mol. Formula
C36H71NO3
Mol. Weight
566
Qty 1
100mg
Appearance
solid
Application Notes
98+% TLC, GC
Synonym
N-C18:0-D-erythro-Ceramide; N-Stearoyl-D-erythro-sphingosine
Solubility
chloroform, hot ethanol, chloroform/methanol, 2:1(up to 5mg/ml)
Storage condition
-20°C
References

1. S. Koybasi et al. “Defects in Cell Growth Regulation by C18:0-Ceramide and Longevity Assurance Gene 1 in Human Head and Neck Squamous Cell Carcinomas” Journal of Biological Chemistry, Vol. 279(43) pp. 44311-44319, 2004
2. J. M. Hauser, B. M. Buehrer, and R. M. Bell “Role of ceramide in mitogenesis induced by exogenous sphingoid bases.” Journal of Biological Chemistry Vol. 269 pp. 6803, 1994
3. N. S. Radin, “Killing tumours by ceramide-induced apoptosis: a critique of available drugs” Biochemical Journal, Vol. 371 pp. 243-256, 2003
4. N. S. Radin, “Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria” Bioorganic and Medicinal Chemistry, Vol. 11(10) pp. 2123-2142, 2003
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