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Cat. Number
H1901
Chemical Name
H1901 N-乙酰基神经鞘氨醇 N-Acetyl-D-erythro-sphingosine 3102-57-6
CAS Number
3102-57-6
Category
synthetic
Mol. Formula
C20H39NO3
Mol. Weight
342
Qty 1
10mg
Appearance
solid
Application Notes
98+% TLC, GC
Synonym
N-C2:0-D-erythro-Ceramide
Solubility
chloroform, ethanol,methanol, DMSO (up to 5 mg/ml)
Storage condition
-20°C
References

1. N. Di Nardo et al. “Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes” British Journal of Dermatology, Vol. 143 pp. 491-497, 2000
2. K. Wong, X. Li, N. Hunchuk “N-Acetylsphingosine (C2-ceramide) Inhibited Neutrophil Superoxide Formation and Calcium Influx” Journal of Biological Chemistry, Vol. 270 pp. 3056-3052, 1995
3. N. S. Radin, “Killing tumours by ceramide-induced apoptosis: a critique of available drugs” Biochemical Journal, Vol. 371 pp. 243-256, 2003
4. N. S. Radin, “Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria” Bioorganic and Medicinal Chemistry, Vol. 11(10) pp. 2123-2142, 2003
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