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Cat. Number
H1857-001
Chemical Name
H1857-001 N-Hexanoyl-NBD-L-threo-sphingosine
Category
synthetic
Mol. Formula
C30H49N5O6
Mol. Weight
575
Qty 1
1mg
Appearance
solid
Application Notes
98+% TLC
Synonym
N-C6:0-NBD-Ceramide; N-C6:0-NBD-L-threo-Sphingosine
Solubility
ethanol, methanol, chloroform
Storage condition
-20°C
References

1. A. Rosenwald and R. Pagano “Inhibition of glycoprotein traffic through the secretory pathway by ceramide” Journal of Biological Chemistry, Vol. 268 pp. 4577-4579, 1993
2. N. Lipsky, R. Pagano “Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: Endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the golgi apparatus en route to the plasma membrane” Journal of Cell Biology, Vol. 100 pp. 27-34, 1985
3. W. Jarvis et al. “Induction of Apoptosis and Potentiation of Ceramide-mediated Cytotoxicity by Sphingoid Bases in Human Myeloid Leukemia Cells” The Journal of Biological Chemistry, Vol. 271 pp. 8275-8284, 1996
4. C. Chalfant et al. “Long Chain Ceramides Activate Protein Phosphatase-1 and Protein Phosphatase-2A Activation is Stereospecific and Regulated by Phosphatidic Acid” The Journal of Biological Chemistry, Vol. 274 pp. 20313-20317, 1999
5. S. Laulederkind et al. “Ceramide Induces Interleukin 6 Gene Expression in Human Fibroblasts” The Journal of Experimental Medicine, Vol. 182 pp. 599-604, 1995
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