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Cat. Number
HMYB01500
Chemical Name
Nicotinamide 烟酰胺
CAS Number
98-92-0
Mol. Formula
C6H6N2O
Mol. Weight
122.12644
Qty 1
500mg
Application Notes
HPLC≥99.0%
Synonym
 Niacinamide;Nicotinic acid amide;Pyridine-3-carboxylic acid amide;Vitamin PP;Vitamin B3
References

Nicotinamide 烟酰胺,是b族维生素家族的重要成员。它是烟酸的衍生物,有时被称为维生素B3。烟酰胺是一种水溶性维生素,这意味着它不会储存在体内,必须定期从饮食来源或补充剂中摄入。它参与许多细胞过程,包括能量代谢、DNA修复和基因表达。烟酰胺已被研究其潜在的治疗应用,包括治疗糖尿病、神经退行性疾病和癌症。

Nicotinamide烟酰胺可抑制 SIRT2 的体外活性,其 EC50 值为 2μM。 烟酰胺可抑制 90% 的黑色素瘤细胞数量,并增加细胞内 NAD+、ATP、ROS 水平。烟酰胺抑制黑色素瘤小鼠的肿瘤生长并提高生存率,可用于黑色素瘤等皮肤癌相关的研究。


订购信息:

产品名称纯度规格
Nicotinamide烟酰胺>99%500mg
Nicotinamide烟酰胺>99%5g
Nicotinamide烟酰胺>99%50g


产品信息:

CAS RN98-92-0
Product NameNicotinamide
Molecular FormulaC6H6N2O
Molecular Weight122.12g/mol
IUPAC Namepyridine-3-carboxamide
InChIInChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI KeyDFPAKSUCGFBDDF-UHFFFAOYSA-N
SMILESC1=CC(=CN=C1)C(=O)N
Canonical SMILESC1=CC(=CN=C1)C(=O)N
AppearanceNicotinamide is a white powder. (NTP, 1992),DryPowder; OtherSolid,Solid,WHITE CRYSTALLINE POWDER.
Boiling Point302 to 320 °F at 760 mm Hg (NTP, 1992)
157 °C at 5.00E-04 mm Hg
Color/FormWhite, powder, needles from benzene
Colorless crystalline solid
White, crystalline powder
Colorless needles
Density1.4 (NTP, 1992)
1.400 g/cu cm at 25 °C
1.4 g/cm³
Flash Point182 °C
Melting Point264 to 268 °F (NTP, 1992)
130 °C
130.0 °C
Mp 129-130 °
128.8 °C
130°C
127-131 °C
Other CAS RN98-92-0
11032-50-1
Physical DescriptionNicotinamide is a white powder. (NTP, 1992)
DryPowder;  OtherSolid
Solid
WHITE CRYSTALLINE POWDER.
PictogramsIrritant
Shelf LifeStable under recommended storage conditions.
... Niacinamide is incompatible with alkalis and strong acids.
Solubilitygreater than or equal to 100 mg/mL at 70° F (NTP, 1992)
500000 mg/L (at 25 °C)
4.09 M
500 mg/mL at 25 °C
In water, 5X10+5 mg/L at 25 °C
Very soluble in water;  1 g is soluble in 1 mL water
1 g dissolves in about 1 mL water, in 10 mL glycerol, in about 1.5 mL alcohol
Soluble in butanol, chloroform
Very soluble in 95% ethanol. Soluble in butanol, amyl alcohol, ethylene glycol, acetone and chloroform;  slightly soluble in ether or benzene
Very soluble in ethanol, glycerol;  slightly soluble in chloroform
Solubility in water, g/100ml at 20 °C: 100 (very good)
2.8 [ug/mL]
Synonyms3 Pyridinecarboxamide;3-Pyridinecarboxamide;B 3, VitaminB3, VitaminEnduramide
Jenapharm, Nicotinsäureamid;Niacinamide;Nicobion;Nicotinamide;Nicotinsäureamid Jenapharm;Papulex;Vitamin B 3;Vitamin B3;Vitamin PP
Vapor DensityRelative vapor density (air = 1): 4.2
Vapor Pressure4.2X10-4 mm Hg at 25 °C (est)
Vapor pressure, kPa at 35 °C: 3.1


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