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Cat. Number
TS2133
Chemical Name
α-Bungarotoxin
CAS Number
11032-79-4
Category
Acetylcholine Nicotinic Receptors
Mol. Formula
C338H529N97O105S11
Mol. Weight
7984.14
Qty 1
1mg
Appearance
White lyophilised solid
Application Notes
99% HPLC
Synonym
a-Bgtx

a-BuTX

Solubility
Soluble in water
References

Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).

Prevents opening of nicotinic receptor-associated ion channels and is selective for α7 receptors over α3β4 receptors (IC50 values are 1.6 nM and > 3 μM respectively).

IVCHTTATSPISAVTCPPGENLCYRKMWCDAFC SSRGKVVELGCAATCPSKKPYEEVTCCSTDKCN PHPKQRPG

(Modifications: Disulfide bridge between 3 - 23, 16 - 44, 29 - 33, 48 - 59, 60 - 65)

下一个:α-conotoxin IMI 上一个:URB 597 (KDS-4103)
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