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| Cat. Number | 288120948699539 |
| Chemical Name | ATC 0065 |
| CAS Number | [510732-84-0] |
| Mol. Formula | C25H29BrF3N5O.2HCl |
| Mol. Weight | 625.35 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N2-[cis-4-[[2-[4-Bromo-2-(trifluoro methoxy)phenyl]ethyl]amino]cyclohexyl]-N4,N4-dimet hyl-2,4-quinazolinediamine dihydrochloride |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Desiccate at RT |
| References | Orally active, potent and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 15.7 nM) that displays > 96-fold selectivity over MCH2. Exhibits antidepressant and anxiolytic activity in vivo. Also displays affinity for 5-HT1A and 5-HT2B receptors (IC50 values are 62.9 and 266 nM respectively). Purity: >98 % |
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