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| Cat. Number | 288020140103659 |
| Chemical Name | AS 1949490 |
| Mol. Formula | C20H18ClNO2S |
| Mol. Weight | 371.88 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-[(4-Chlorophenyl)methoxy]-N-[(1S) -1-phenylethyl]thiophene-2-carboxamide |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at RT |
| References | Selective SHIP2 (SH2 domain-containing inositol 5'-phosphatase 2) inhibitor (IC50 values are 0.34 μM and 0.62 μM for mouse and human respectively); displays approximately 30-fold affinity for SHIP2 over SHIP1. Increases insulin-induced phosphorylation of Akt in L6 myotubules. Stimulates activation of glucose metabolism; regulates gluconeogenesis in vitro and in vivo and exhibits antidiabetic effects. Purity: >99 % |
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