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Cat. Number
287905649371960
Chemical Name
Arcyriaflavin A
CAS Number
[118458-54-1]
Mol. Formula
C20H11N3O2
Mol. Weight
325.32
Qty 1
10mg
Synonym
12,13-Dihydro-5H-indolo[2,3-a]pyrro lo[3,4-c]carbazole-5,7(6H)-dione
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at -20°C
References
Potent inhibitor of cdk4/cyclin D1 (IC50 = 59 nM). Also active against CaM kinase II (IC50 = 25 nM) but displays selectivity over several other kinases in vitro (IC50 values for inhibition of PKA and PKC are > 2 and > 100 μM respectively). Inhibits human cytomegalovirus (HCMV) replication in vitro (IC50 = 200 nM).
Purity: >98 %
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